Saturday 30 November 2013

Central Serous Retinopathy: CSR

WHAT IS CSR?

Central serous retinopathy (CSR) is a condition of unknown cause in which serous fluid ( thin and serum like fluid ) accumulates underneath the central part of the retina ( light sensitive part of the eye ). This fluid collection is similar to blisters caused on the skin when exposed to boiling water. This fluid collection beneath it causes the retina to become elevated. The elevation produces a change in the layout of the light sensors in the eye leading onto distorted and blurred vision.

WHO GETS CSR?

Most patients with CSR are males in their third and fourth decades. Stress or corticosteroid use may play roles in inciting or aggravation the condition. Intake of systemic steroids for Asthma and steroid containing ointments for skin disorders can also predispose to CSR. Hypertension and Caffeine use has also been implicated in CSR.

CSR is more common in anxious and stressed out persons. It can occur after a period of intense stress like divorce or loss of job.

WHAT ARE THE SYMPTOMS OF CSR?

Many patients first notice a minor blurring of vision, followed by various degrees of:
  • metamorphopsia (defective, distorted vision)
  • micropsia (distorted visual perception in which objects appear smaller than their actual size)
  • chromatopsia (visual defect in which objects appear unnaturally colored)
  • central scotoma
  • increasing hyperopia (farsightedness)
Visual acuity in the acute stage may range from 20/20 to 20/200 and averages 20/30. In some patients the onset of symptoms is preceded or accompanied by migraine-like headaches.


WHAT IS THE NATURAL COURSE OF CSR?

When left alone, central serous retinopathy heals spontaneously within 4 to 8 weeks, with full recovery of visual acuity. However, about one-third to one-half of all patients have recurrences after the first episode of the disease; 10 percent have three or more recurrences. In almost half of the patients, the recurrence is within one year of the primary episode, but relapses may occur up to ten years later.

Central serous choroidopathy usually affects just one eye at a time, but it is possible that both eyes may be affected at the same time.



WHAT TESTS MUST BE DONE?

The diagnosis is made by an eye examination, sometimes using a fundus contact lens. The diagnosis is confirmed by fluorescein angiography. In this test, an orange dye is injected into the patient’s vein, and this dye is observed as it circulates through the ocular vasculature. Typically the fluorescein enters into the blister and stains its contents, identifying one or more leakage points. Often, areas of previous retinal pigment epithelial disruption can be visualized elsewhere in the same eye or in the macula of the unaffected eye. Ocular coherence tomography (OCT) is another test that is helpful. This imaging modality can accurately detect fluid and swelling in the retina.



HOW DO WE TREAT CSR?            

The typical patient with central serous retinopathy does not require treatment. Most episodes of this condition are self-limited and resolve within 2 to 3 months. Simple reassurance to the patient that this will occur is beneficial. In some patients, the subretinal fluid persists for longer than this time period, and, in this setting, treatment is recommended. Thermal laser can be applied to the area of the retinal pigment epithelium that is thought to be playing a role in fluid accumulation.  Usually, this treatment is quite effective and can be very useful when the area of leakage is well away from the center of vision.  Many patients will recover vision back to the 6/6 level, however, patients will often report that vision in the affected eye is not quite as good as the normal eye even long after the fluid has resolved. Approximately 25% of patients develop a recurrent episode. There is also a subset of patients with significant retinal pigment epithelial abnormalities that are predisposed to attacks in both eyes, often simultaneously, and the prognosis in this group is much less optimistic, though with treatment many can maintain reading and driving vision.

WHAT CAN YOU DO TO PREVENT RECURRENCE?

If you have had an attack of CSR you have a high chance of having a recurrence. To lower the risk of recurrence:

  • ·         Learn relaxation techniques like yoga and meditation.
  • ·         Try to find solution to constant stressors in life
  • ·         Exercise daily
  • ·         Totally abstain from smoking
  • ·         Loose body weight if you are over weight